Clinical management of acute myocarditis associated with systemic sclerosis using high dose intravenous immunoglobulin

Systemic   Sclerosis  ( SSc )  is an  autoimmune  disorder  associated  with  diffuse  vascular  lesions  that  involves  skin  and  many  internal  organs  including  heart. Cardiac  involvements  include  pulmonary  hypertension ,  fibrosis  and  myocarditis ( 1-3)

Pulmonary hypertension associated with systemic sclerosis

Pulmonary arterial hypertension (PAH) was considered as the leading cause of morbidity and mortality in systemic sclerosis (SSc) in the last two decades .The patients with SSc and PAH have about 50-60% estimated 3 year survival. There is proliferation and contraction of smooth muscle cells of the pulmonary arterioles in PAH.1